High Incidence of Telaprevir-associated Severe Rash Leading to Discontinuation
نویسندگان
چکیده
منابع مشابه
Severe neonatal hyperbilirubinemia leading to exchange transfusion
Background :Severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. This study was conducted to investigate the causes of severe hyperbilirubinemia leading to Exchange Transfusion (ET) from March 2009 to March 2011 in Bahrami children hospital, Tehran, Iran in order to establish guidelines to prevent profound jaundice & ET. Methods : 94 neonates underwent ...
متن کاملsevere neonatal hyperbilirubinemia leading to exchange transfusion
background :severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. this study was conducted to investigate the causes of severe hyperbilirubinemia leading to exchange transfusion (et) from march 2009 to march 2011 in bahrami children hospital, tehran, iran in order to establish guidelines to prevent profound jaundice & et. methods : 94 neonates underwent et...
متن کاملAN UNUS UAL PRESENTATION OF LEECH LEADING TO SEVERE HEMAT EMESIS IN AN INFANT
A nine month old infant was taken to a rural medical center due to hematemesis and melena. The bleeding persisted in spite of active management with gastric lavage, intravenous cimetidine, antiacid therapy and blood transfusion for four days' duration. The patient was referred to our center for further evaluation and management. On arrival he was pale and ill looking with active bleeding fr...
متن کاملDermatological side effects of hepatitis C and its treatment: patient management in the era of direct-acting antivirals.
Dermatological adverse events (AEs) are an existing concern during hepatitis C virus (HCV) infection and peginterferon/ribavirin treatment. HCV infection leads to dermatological and muco-cutaneous manifestations including small-vessel vasculitis as part of the mixed cryoglobulinemic syndrome. Peginterferon/ribavirin treatment is associated with well-characterized dermatological AEs tending towa...
متن کاملManagement of anorectal symptoms associated with telaprevir.
PJP Based on my clinical experience with telaprevir (Incivek, Vertex), I would say that anorectal symptoms occur 25–30% of the time. The package insert for telaprevir cites a similar figure, reporting anorectal symptoms in 29% of telaprevir-treated patients compared to only 7% of patients treated with peginterferon and ribavirin. Overall, approximately one fourth of patients seem to experience ...
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ژورنال
عنوان ژورنال: Journal of Clinical and Experimental Hepatology
سال: 2013
ISSN: 0973-6883
DOI: 10.1016/j.jceh.2012.12.002